Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

This Week's Must Reads

Vascular Risk Linked with Cognitive Decline, JAMA Neurology; ePub 2018 May 21; Rabin, et al

Guillain-Barré, Zika Virus, and Morbidity, JAMA Neurology; ePub 2018 May 21; Dirlikov, et al

PFO Closure Linked with Reduced Recurrent Stroke , J Stroke Cerebrovasc Dis; ePub 2018 May 24; Garg, et al

Integrated MRI and [11C]‐PBR28 PET Imaging in ALS, Ann Neurol; ePub 2018 May 8; Alshikho, et al

Low Calcium, Magnesium Levels and Aneurysm Rupture, Stroke; ePub 2018 May 29; Can, Rudy, Castro, et al

Rare Diseases

FDA Approves Hizentra for CIDP Treatment, CSL Behring news release; 2018 Mar 16

Cerebral Cavernous Malformation in the Elderly , JAMA Neurol; ePub 2017 May 8; Flemming, et al

Read more in Rare Diseases

Parkinson's Disease

Orthostatic Hypotension in PD Increases Care Costs, Parkinsonism Relat Disord; ePub 2017 Nov 27; Merola, et al

FDA Approves Vercise Deep Brain Stimulation System, Boston Scientific news release; 2017 Dec 11

Read more in Parkinson's Disease

Movement Disorders

Restless Legs Syndrome, CVD Linked in Women, Neurology; ePub 2017 Dec 15; Li, Li, Winkelman, et al

Cognitive Impairment in PSP Linked with Tau Burden, Mov Disord; ePub 2017 Oct 30; Koga, Parks, et al

Read more in Movement Disorders

Traumatic Brain Injury

TBI Linked with 2-fold Increase Risk of Dementia, JAMA Neurology; ePub 2018 May 7; Barnes, et al

Rehospitalization, Participation 5 Years Post-TBI, J Head Trauma Rehab; ePub 2018 Mar 29; Erler, et al

Read more in Traumatic Brain Injury

Practice Management

Neurologic Drug Shortages May Compromise Care, Neurology; ePub 2017 Nov 15; Omorodion, et al

Racial Disparities in Neurologic Care Examined, Neurology; ePub 2017 May 17; Saadi, et al

Read more in Practice Management

Mixed Topics

Epilepsy, Fertility, and Birth Outcomes Examined , JAMA Neurology; ePub 2018 Apr 30; Pennell, et al

Sickle Cell Trait, Ischemic Stroke Link Examined, JAMA Neurology; ePub 2018 Apr 23; Hyacinth, et al

Read more in Mixed Topics

Headache & Migraine

Prevalence of Optic Nerve Head Edema in the ED, Neurology; ePub 2018 Jan 5; Sachdeva, et al

Association Between Migraine and Suicidal Behavior, Headache; ePub 2017 Nov 29; Friedman, Zhong, et al

Read more in Headache & Migraine

Trauma

Effects of Concussion, Blast Exposure Examined , Neurology; ePub 2017 Oct 13; Tsao, Stentz, et al

Read more in Trauma

Stroke

PFO Closure Linked with Reduced Recurrent Stroke , J Stroke Cerebrovasc Dis; ePub 2018 May 24; Garg, et al

Low Calcium, Magnesium Levels and Aneurysm Rupture, Stroke; ePub 2018 May 29; Can, Rudy, Castro, et al

Read more in Stroke

Pain

FDA Approves Expanded Use of Exparel Nerve Block, Pacira news release; 2018 Apr 6

FDA Approves Apadaz for Acute Pain Relief, KemPharm, Inc. news release; 2018 Feb 23

Read more in Pain