Study of Human Parechovirus in U.S. Finds 7% Prevalence

Major Finding: Of 780 enterovirus RNA–negative CSF samples taken during 2006-2008, RT-PCR detected HPeV in 2% of 218 samples from 2006, 17% of 320 from 2007, and in none of 242 from 2008. A separate case report found abdominal distension in 6 of 8 infants with HPeV.

Data Source: Retrospective RT-PCR analysis of frozen CSF samples from a 3-year period in the larger study, and a case report of eight infants.

Disclosures: The Kansas City study was supported by research residual funds from Dr. Selvarangan. Dr. Selvarangan said he had no other relevant financial disclosures. Dr. Bangalore said he had no relevant financial disclosures.