Three regular meals a day is best in T2DM

The findings caught the attention of her audience. One endocrinologist said that “patients always ask me about doing six small meals a day.”

Most of the mean blood glucose reduction found in the 3m group happened after only 14 days on the diet, suggesting an improvement in hepatic insulin sensitivity. There was no correlation between glucose levels and weight; the beneficial effects of the 3m diet appeared independent of weight loss.
Those benefits instead might attributable to effects on “clock genes,” which control the circadian oscillation of gene expression. The investigators are looking into the matter further. Two meals per day also has been shown to help in type 2, but the investigators preferred the three-meal approach because it’s more in line with how people actually live.

The funding source was not reported. Dr. Jakubowicz, author of “The Big Breakfast Diet” (Workman Publishing Co., 2009), had no other disclosures. The other investigators had no disclosures.

aotto@frontlinemedcom.com

SOURCE: Jakubowicz D et al. ENDO 2018, Abstract OR05-2.