Neurology
News from the FDA/CDC
FDA committee rejects oxycodegol, new opioid designed for less abuse
A novel opioid molecule designed to have less abuse potential with slower CNS entry received a unanimous FDA committee turn down.
From the Journals
Half of SLE patients have incident neuropsychiatric events
Average 8-year follow-up of an international lupus inception cohort showed that 52% developed a neuropsychiatric event.
Savvy Psychopharmacology
Valproic acid-induced hyperammonemic encephalopathy
Hyperammonemia can occur in individuals receiving VPA and is most often asymptomatic.
From the Journals
Data point to bidirectional link between sleep disorders and ADHD
Investigators found a dose-response relationship between sleep duration and the odds of having ADHD symptoms.
FDA/CDC
FDA okays ubrogepant for acute migraine treatment
ACHIEVE I and ACHIEVE II demonstrate efficacy.
Conference Coverage
First autoimmune epilepsy RCT supports IVIG therapy
BALTIMORE – Misdiagnosis and delayed treatment may mean that patients end up in nursing homes diagnosed with Alzheimer’s disease.
Conference Coverage
Could preventing dementia be as simple as following your mom’s advice?
SAN DIEGO – Emerging evidence agrees: Lots of exercise, a good diet, and social interaction are good for both body and mind.
Conference Coverage
Pimavanserin reduced dementia-related psychotic symptoms without affecting cognition
SAN DIEGO – The adverse event profile of the second-generation antipsychotic appears more benign than that typically seen with antipsychotics in...
Conference Coverage
Addiction specialists: Cannabis policies should go up in smoke
SAN DIEGO –
Conference Coverage
Positive functional results reported for aducanumab in a pooled, post hoc analysis
SAN DIEGO – The results might give patients “an extra year or 2” of independence, said one clinical investigator in an aducanumab trial.
From the Journals
Researchers describe first cases of episodic visual snow associated with migraine
A series of migraine patients with episodic visual snow makes case for a condition that is distinct from visual snow syndrome.