Schizophrenia & Other Psychotic Disorders
From the Journals
Schizophrenia, bipolar disorder associated with increased risk of secondary TD
Patients with schizophrenia and bipolar disorder were four to five times more likely to also have tardive dyskinesia.
Hard Talk
Sequential intercept model is really a ‘no-intercept model’
“I have not yet been asked by anyone if the amount of care a patient is obtaining is too fragmented,” Dr. Nicolas Badre writes.
Conference Coverage
Pimavanserin reduced dementia-related psychotic symptoms without affecting cognition
SAN DIEGO – The adverse event profile of the second-generation antipsychotic appears more benign than that typically seen with antipsychotics in...
Shrink Rap News
The Great Pretender
Despite her book’s shortcomings, the author wrote an amazing story about the Rosenhan study, Dr. Dinah Miller writes.
From the Journals
Prosody recognition associated with functioning in first-episode schizophrenia
"These findings are consistent with the view that emotion recognition deficits could be contributing to deficits in the ability of people with...
Evidence-Based Reviews
Black-box warnings: How they can improve your clinical practice
A better understanding of these warnings leads to safer, more effective prescribing.
FDA/CDC
Alkermes submits NDA for new schizophrenia, bipolar I treatment
Data from the ENLIGHTEN-1 and ENLIGHTEN-2 studies are included in the application for ALKS 3831, a combination of olanzapine and samidorphan.
Conference Coverage
Will paying patients to take oral antipsychotics boost adherence?
COPENHAGEN – Economic incentives have been shown to improve adherence to long-acting injectable antipsychotics.
From the Journals
Resting-state cerebral blood flow tied to apathy in schizophrenia
“The paucity of reported associations between striatal rCBF and negative symptoms could result from the fact that until now apathy and diminished...
From the Journals
COGS update shows viability of endophenotypes in schizophrenia research
"As stable biomarkers of the underlying brain dysfunctions, endophenotypes hold promise for parsing clinical heterogeneity of schizophrenia and...
Commentary
Should psychiatrists prescribe nonpsychotropic medications?
In certain scenarios, prescribing a nonpsychotropic medication is the logical choice.