Alzheimer's & Cognition
News from the FDA/CDC
FDA issues warnings to companies selling illegal Alzheimer’s treatments
The FDA targeted more than 58 products.
From the Journals
Novel plasma biomarkers may predict preclinical Alzheimer’s disease
The approach will need to be validated and translated “to a simpler automated platform suitable for wider utility.”
Evidence-Based Reviews
Can lifestyle modifications delay or prevent Alzheimer’s disease?
Evidence suggests combining lifestyle modifications may yield better cognitive outcomes.
What Your Patients are Hearing
Charting a life with Alzheimer’s disease
Interviews with couple chronicle the devastating impact the disease can have on families.
Feature
Phase 3 studies of antiamyloid Alzheimer’s drug crenezumab stopped
The molecule will continue to be tested in a study of familial Alzheimer’s in Colombia.
Conference Coverage
Mild cognitive impairment risk slashed by 19% in SPRINT MIND
Clinicians are calling blood pressure drugs the first disease-modifying therapy for MCI.
News
Frailty may affect the expression of dementia
People with higher degrees of frailty may be more likely to have more Alzheimer’s disease pathology and clinical dementia.
Evidence-Based Reviews
Neuropsychiatric symptoms of dementia: Monotherapy, or combination therapy?
A cholinesterase inhibitor plus memantine may be more effective than either medication alone.
News
As deep sleep decreases, Alzheimer’s pathology – particularly tau – increases
EEG studies and brain imaging concur: Disrupted sleep patterns are associated with tau and amyloid in Alzheimer’s-affected regions and...
Cases That Test Your Skills
Sudden-onset memory problems, visual hallucinations, and odd behaviors
Ms. D, age 62, is disoriented, distractible, tearful, and tangential. She reports that 'aerialists' are climbing through her windows at night and...
Latest News
Treating OSA with positive airway pressure decreased amyloid levels in CSF
The finding hints that improving obstructive sleep apnea in mid-life could reduce the later risk of Alzheimer’s disease.