Geriatrics
Latest News
Biogen, Eisai discontinue aducanumab Alzheimer’s trials
All trials – the phase 3 ENGAGE and EMERGE trials, phase 2 EVOLVE safety study, and the long-term extension of the phase 1b PRIME study – have...
Commentary
Boosting Alzheimer’s trial participation via Medicare Advantage ‘memory fitness programs’
Dr. Richard J. Caselli comments on a new initiative from the Global Alzheimer’s Platform (GAP) Foundation.
News from the FDA/CDC
FDA issues warnings to companies selling illegal Alzheimer’s treatments
The FDA targeted more than 58 products.
From the Journals
Novel plasma biomarkers may predict preclinical Alzheimer’s disease
The approach will need to be validated and translated “to a simpler automated platform suitable for wider utility.”
Feature
Phase 3 studies of antiamyloid Alzheimer’s drug crenezumab stopped
The molecule will continue to be tested in a study of familial Alzheimer’s in Colombia.
From the Journals
Potential antidepressant overprescribing found in 24% of elderly cohort
Overprescribing of SSRIs accounted for 74% of all antidepressant overprescriptions, followed by mirtazapine (19%).
News
Frailty may affect the expression of dementia
People with higher degrees of frailty may be more likely to have more Alzheimer’s disease pathology and clinical dementia.
Daily News Podcast
Deep sleep decreases, Alzheimer’s increases
There is reassuring data on pregnancy outcomes for women with atopic dermatitis.
Daily News Podcast
AAP guidance: How to ask about military service
Neudexta is mainly being prescribed for dementia and Parkinson’s.
Conference Coverage
Researchers exploring ways to mitigate aging’s impact on diabetes
LOS ANGELES – Potential preventative measures include caloric restriction, exercise, and taking metformin.
From the Journals
Antidepressants tied to greater hip fracture incidence in older adults
In the year after initiating antidepressant therapy, a 3.5% incidence rate for hip fractures was found, compared with 1.3% in the control group....