Geriatrics
Feature
Dr. Paul Aisen Q&A: Aducanumab for Alzheimer’s
A leading Alzheimer’s researcher, Dr. Aisen answers some questions about the resurrection of aducanumab as a potential therapy for Alzheimer’s...
Feature
Biogen plans to submit application to FDA for Alzheimer’s drug aducanumab
The company’s hopes lie with a secondary analysis of high-dose patients from two failed trials.
Conference Coverage
Agitation in psychosis: Still no ‘magic bullet’
SAN DIEGO – Some evidence supports various treatments, including antipsychotics, Dr. Marc Agronin said.
From the Journals
How does alcohol intake affect dementia risk in older adults?
The association may be more consistently adverse in adults with mild cognitive impairment.
Conference Coverage
Benzodiazepines, hypnotics don’t increase Alzheimer’s pathology
LOS ANGELES – The drugs were not associated with Alzheimer’s pathology, but were associated with a trend toward greater loss of neurons in the...
Conference Coverage
Transdermal estradiol may modulate the relationship between sleep, cognition
LOS ANGELES – Women using the patch fared better in all measures than did those taking oral conjugated equine estrogen.
Conference Coverage
Gum bacteria and Alzheimer’s: A hypothesis inches forward
LOS ANGELES – Results from a small trial saw neutralizing P. gingivalis associated with biomarker changes; a larger trial is planned.
Conference Coverage
Hypertension, white matter hyperintensities, and dementia: What’s the link?
LOS ANGELES – Findings from a French cohort suggest that a vascular pathway, independent of amyloid, bears on cognitive decline.
Conference Coverage
Alzheimer’s disease raises risk for recurrent seizures
LOS ANGELES – In one cohort study, nearly 70% of Alzheimer’s disease patients who had one seizure had another within months, and seizures were...
Conference Coverage
Misguided fear is keeping benzodiazepines from elderly
SAN FRANCISCO – Benzos are “wonderful” for geriatric anxiety and anxiety-related insomnia, said Dr. Carl Salzman of Harvard Medical School.
From the Journals
Anticholinergic drugs linked to dementia in older populations
“Associations were stronger in [dementia] cases diagnosed before the age of 80 years,” the researchers noted.