Depression
From the Journals
Novel agent promising for major depression: Phase 3 data
The study adds to evidence suggesting zuranolone is a promising novel therapy for treating MDD.
Conference Coverage
No apparent drug interaction with ozanimod and antidepressants
Patients with MS who are taking SSRIs or SNRIs had lower rates of hypertension and adverse events potentially related to serotonin than patients...
From the Journals
Alcohol dependence in teens tied to subsequent depression
There was no evidence that frequency or quantity of alcohol consumption at age 18 was significantly associated with depression at age 24.
From the Journals
B vitamin may help boost antidepressant efficacy
“This is a ‘shortcut’ that gets directly to the brain,” said Dr. Vladimir Maletic.
From the Journals
Anxiety, your brain, and long COVID: What the research says
Anxiety, depression, and COVID-19 can be a bad combination for your brain and your long-term health.
From the Journals
Molecular mechanisms may predict major depressive disorder
Six miRNAs distinguished depressed patients from healthy controls with reasonable accuracy and could act as biomarkers in research and treatment...
Conference Coverage
Suicidality risk in youth at highest at night
The findings “signal potentially that there’s a need for support, particularly at nighttime, and that there might be a potential of targeting self...
From the Journals
Ketamine may be a viable alternative to ECT for severe depression
This was an “extraordinarily important and clinically relevant study, large, well-designed, and well-conducted,” said Dr. Dan Iosifescu.
Conference Coverage
Treatment-resistant depression? Don’t forget about MAOIs
Psychiatrists urge colleagues to ignore myths about venerable drugs and consider them in appropriate patients.
From the Journals
Peak seasons, times for suicidal thoughts, attempts identified
“Most people incorrectly assume that suicide behaviours peak in winter and are surprised, as I was, when learning about this phenomenon, that...
Conference Coverage
Prenatal sleep problems, depression linked to poorer outcomes
Screening pregnant patients for sleeping problems and for prenatal depression early in pregnancy may help identify and prevent later problems.