Depression
From the Journals
Four genetic variants link psychotic experiences to multiple mental disorders
Schizophrenia might not be sole driving force behind psychosis
Conference Coverage
Esketamine nasal spray may get expanded indication
COPENHAGEN – Primary endpoint met in two phase 3 pivotal trials in patients with major depressive disorder symptoms at imminent risk for suicide...
Conference Coverage
Latest suicide prevention research highlights roles for clinicians, teachers, and parents
“Belongingness to parents” in particular predicted lower odds of suicidal ideation in high school students in one study.
Conference Coverage
Statins may do double duty as antidepressants
COPENHAGEN – Mounting evidence suggests antidepressant efficacy for statins in immunometabolic-related depression.
Conference Coverage
Oral drug for postpartum depression aces phase 3 trial
COPENHAGEN – “I think this changes the paradigm in the treatment of postpartum depression,” said Dr. Eduard Vieta.
From the Journals
SAGE-217 shows reduction in depression with no safety concerns
A new oral antidepressant targeting GABAA receptors shows significant improvements in depression scores with no major safety signals....
Out Of The Pipeline
Brexanolone injection for postpartum depression
First-in-class neuroactive steroid was recently FDA-approved for treating adults with postpartum depression.
Evidence-Based Reviews
Antidepressants for pediatric patients
Optimal prescribing depends on a thorough understanding of these agents’ efficacy and safety.
Pearls
DBS vs TMS for treatment-resistant depression: A comparison
This article compares DBS and TMS, and offers suggestions for educating patients about the potential adverse effects and therapeutic outcomes of...
Commentary
‘Miracle cures’ in psychiatry?
“I take very small doses of it regularly against depression and against indigestion, and with the most brilliant success.... it is only now that I...
Latest News
FCC backs designating 988 as suicide prevention hotline
The report submitted to Congress says the new three-digit number “could be more effective” at prevention than the current 10-digit one.