Dementia Officially Replaced by Major Neurocognitive Disorder, per DSM-5

Elevated homocysteine and C-reactive protein levels are implicated in cardiovascular disease and also increasingly under scrutiny in Alzheimer’s disease. High homocysteine levels can be readily lowered with folate, and 81 mg/day of aspirin may be sufficient to reduce C-reactive protein, he added.

Delirium is the one neurocognitive disorder that is essentially unchanged from DSM-IV, according to Drs. McCall and Grossberg. This condition is characterized by rapid onset and fluctuations in severity during the day and must be linked to the physiologic consequences of a medical condition.

—Bruce Jancin