Combining AEDs With Different Mechanisms of Action May Lead to Optimal Treatment Outcome
Neurology Reviews. 2013 July;21(7):14
July 10, 2013 | Neurology Reviews
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—Erik Greb
Senior Associate Editor
Suggested Reading
Brodie MJ, Sills GJ. Combining antiepileptic drugs—rational polytherapy? Seizure. 2011;20(5):369-375.
Giussani G, Beghi E. Does mechanism of drug action matter to inform rational polytherapy in epilepsy? CNS Neurol Disord Drug Targets. 2013 Feb 27 [Epub ahead of print].
Kaminski RM, Matagne A, Patsalos PN, Klitgaard H. Benefit of combination therapy in epilepsy: a review of the preclinical evidence with levetiracetam. Epilepsia. 2009;50(3):387-397.
