Biomarkers Linked to L-Methylfolate Effectiveness for Depression
June 20, 2012|Internal Medicine News
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AT A MEETING OF THE NEW CLINICAL DRUG EVALUATION UNIT SPONSORED BY THE NATIONAL INSTITUTE OF MENTAL HEALTH
The findings represent a "consistent signal suggesting that something is going on with respect to the metabolic, inflammatory, and oxidative profile of some patients that renders them ... particularly susceptible to the therapeutic effects of L-methylfolate as adjunctive therapy above and beyond placebo," Dr. Papakostas said, stressing that confirmatory trials are needed.
These studies were supported by a grant from PamLab. Dr. Papakostas and Dr. Stahl disclosed financial relationships with numerous pharmaceutical companies.
