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Late effects in young cancer survivors underscore importance of high-risk screening
Childhood cancer survivors have higher standardized mortality ratios than early-adolescent and young adult cancer survivors.
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Adolescent obesity linked with midlife cancer risk
Investigators say teen obesity could be an important intervention target for subsequent cancer prevention.
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Synovial biopsy findings drive precision medicine for RA closer to the clinic
“I think synovial biopsies will yield a lot of information and really, hopefully, help us target therapy and find new therapeutic targets that we...
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Tramadol use for noncancer pain linked with increased hip fracture risk
"Our results point to the need to consider tramadol's associated risk of fracture in clinical practice and treatment guidelines," the researchers...
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IFN-activated monocytes show early promise for ovarian cancer
ORLANDO - Two of 11 patients achieved a partial response, and there were no grade 4-5 adverse events.
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Model reveals genes associated with prognosis in ER+, HER2– breast cancer
ORLANDO – A model revealed 5 genes associated with poor prognosis and 15 genes associated with good prognosis.
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Phase 2 data: Inotuzumab, approved in adults with B-ALL, shows promise in kids, too
“Importantly, there were no inotuzumab dose modifications or delays due to hepatic toxicity.”
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Adding ilixadencel improved outcomes in metastatic renal cell carcinoma
ORLANDO – Ilixadencel improved responses when added to sunitinib as first-line therapy in patients with synchronous metastatic renal cell...
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The 2019 novel coronavirus: Case review IDs clinical characteristics
A review of coronavirus pneumonia cases in Wuhan, China, suggests older men and those with comormid conditions are most likely to be affected by...
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Deferiprone noninferior to deferoxamine for iron overload in SCD, rare anemias
An oral iron chelator granted accelerated approval for thalassemia is noninferior to deferoxamine for iron overload in patients with sickle cell...
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Psoriasis: A look back over the past 50 years, and forward to next steps
“The progress has been breathtaking – there’s no other way to describe it.”
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Registry data reveal temporal relationship between psoriasis symptoms and PsA onset
ATLANTA – Age at the onset of psoriasis was the main factor that determined PsA symptom synchronicity, according a study of data from the PsART...
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Sevuparin failed for acute VOC in sickle cell, but may have preventive potential
The novel nonanticoagulant heparinoid drug sevuparin may have value in the setting of prodromal vaso-occlusive crisis in patients with SCD.
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Liver fibrosis scores predict CV event risk associated with NAFLD
NAFLD is associated with a twofold increase in cardiovascular events, and liver fibrosis in NAFLD is associated with a fourfold increase.