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PALOMA-3 biomarker analysis: Liquid biopsy could ID progression risk
TP53 mutation, FGFR1 amplification, and tumor purity in plasma each predict early progression on palbociclib and/or fulvestrant in patients with...
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TAILORx: Clinical data add value to recurrence score
CHICAGO – Clinical risk stratification adds prognostic value to the 21-gene recurrence score for guiding treatment selection in patients with...
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PREDIX HER2 trial: Similar efficacy, less toxicity with T-DM1 for HER2+, HR+ breast cancer
T-DM1 had similar efficacy and less toxicity vs. standard chemotherapy for patients with HER2- and HR-positive breast cancers in the phase 2...
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KRISTINE: Three-year data help forge path to T-DM1-based deescalation in HER2+ BC
CHICAGO – T-DM1 plus pertuzumab reduced toxicity in patients with HER2-positive stage I-III breast cancer in the KRISTINE study, but led to lower...
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Nearly two-thirds of gynecologic oncology respondents experienced sexual harassment
CHICAGO – A survey suggests sexual harassment remains rampant in the gynecologic oncology field, with both women and...
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FDA launches call center project to streamline Expanded Access request process
CHICAGO – Project Facilitate is a pilot call center project designed to create a single point of contact with FDA oncology staff who can guide...
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ENZAMET trial: Early enzalutamide delays progression, improves survival in mHSPC
CHICAGO –Enzalutamide with standard first-line testosterone suppression delays progression and improves survival in...
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Ado-trastuzumab highly efficacious for rare HER2-amplified SGCs
CHICAGO – Ado-trastuzumab emtansine, previously known as T-DM1, is highly efficacious in patients with HER2-...
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Pembro with or without chemo superior to EXTREME for advanced HNSCC
CHICAGO – Pembrolizumab with and without chemotherapy proved superior for overall survival vs. the EXTREME regimen...
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FIGO outlines global standards for preeclampsia screening
New FIGO recommendations aim to frame the issues regarding preeclampsia and to suggest key actions to address the health burden it poses.
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Rapid urine test could aid in preeclampsia diagnosis
NASHVILLE, TENN. – The 3-minute GestAssured Test Kit holds promise as an aid in the diagnosis of preeclampsia.
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Targeted sequencing panel IDs Lynch syndrome in women with/at risk for endometrial cancer
NASHVILLE, TENN. – A targeted next-generation sequencing panel rapidly IDs Lynch syndrome pathogenic mutations in...
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Ultrasound or biopsy for evaluation of endometrium? It depends
NASHVILLE, TENN. –
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Immediate postpartum LARC: ‘Agony and ecstasy’
NASHVILLE, TENN. – Dr. Eve Espey: Immediate postpartum LARC has the potential to be transformational – at least once reimbursement issues are...
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TVEC may improve response rates in nonmetastatic TNBC
ATLANTA – Adding TVEC to neoadjuvant chemotherapy improved pCR rates in patients with nonmetastatic TNBC in a phase...