Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

This Week's Must Reads

HCV and Increased Risk of Atherosclerosis, Hepatol Int; ePub 2018 Feb 8; Bridge, et al

Chronic HCV & Early HIV Viral Response to ART, AIDS; ePub 2018 Jan 13; Willis, Cole, et al

Impact of DM/HBV Coinfection in Patients with HCV, J Gastroenterol Hepatol; ePub 2018 Jan 26; Subramaniam, et al

Prevalence of HCV and Route of Transmission, J Viral Hepat; 2018 Feb; Wong, Lee, Ng, et al

Liver Fibrosis & Microbial Translocation in HIV/HCV, J Infect Dis; ePub 2018 Jan 3; Reid, et al

Clinical Guidelines

Low-Dose CT Screening for Lung Cancer, CHEST; ePub 2018 Jan 25; Mazzone, et al

USPSTF Guidelines for HT in Postmenopausal Women, JAMA; 2017 Dec 12; US Preventive Services Task Force

Read more in Clinical Guidelines

Mental Health

Age at Menarche and Depression into Adulthood, Pediatrics; ePub 2017 Dec 26; Mendle, et al

Cognitive Training to Prevent Cognitive Decline, Ann Intern Med; ePub 2017 Dec 19; Butler, et al

Read more in Mental Health

Cardiology

Can Omega-3 Supplement Use Lower CVD Risk?, JAMA Cardiol; ePub 2018 Jan 31; Aung, et al

Adherence Rates to Secondary Prevention Meds, Circulation; ePub 2018 Jan 31; Mathews, et al

Read more in Cardiology

Neurology

Prior Use of NOACs & Mortality in ICH Patients, JAMA; 2018 Feb 6; Inohara, Xian, Liang, et al

Thrombectomy for Stroke Patients at 6 to 16 Hours, N Engl J Med; ePub 2018 Jan 24; Albers, et al

Read more in Neurology

Oncology

Low-Dose CT Screening for Lung Cancer, CHEST; ePub 2018 Jan 25; Mazzone, et al

Risk of Breast Cancer with Hormonal Contraception, N Engl J Med; 2017 Dec 7; Mørch, Skovlund, et al

Read more in Oncology

Geriatrics

Methylphenidate for Apathy in Alzheimer’s Disease, Am J Psychiatry; ePub 2017 Sep 15; Padala, et al

Bisphosphonate Use & Fractures in Older Women, J Am Geriatr Soc; 2017 Sep; Drieling, et al

Read more in Geriatrics

Vaccines

2018 Adult ACIP Immunization Schedule Released, Ann Intern Med; 2018 Feb 6; Kim, Riley, et al

2018 ACIP Immunization Schedule for Children, MMWR; ePub 2018 Feb 6; Robinson, et al

Read more in Vaccines

AML

Azacitidine in Lower-Risk MDS Shows Promise, Oncologist; ePub 2017 Nov 8; Komrokji, et al

Clostridium Difficile Infection in People with MDS, World J Clin Oncol; 2017 Oct 10; Shaht, et al

Read more in AML

Obesity

Bariatric Surgery and All-Cause Mortality, JAMA; 2018 Jan 16; Reges, Greenland, et al

Fiber Supplementation and Metabolic Outcomes, Am J Clin Nutr; 2017 Dec; Thompson, et al

Read more in Obesity

Health Policy

FDA Approval of Intragastric Balloon System, Device assists adults with weight management

FDA Approval for Balloon Device, Non-surgical device treats obesity

Read more in Health Policy

Nephrology

BP Control & Risk of Mortality in Patients with CKD, JAMA Intern Med; ePub 2017 Sep 5; Malhotra, et al

Intensive SBP Lowering & Kidney, CV Outcomes, Ann Intern Med; ePub 2017 Sep 5; Beddhu, et al

Read more in Nephrology

Hepatitis

HCV and Increased Risk of Atherosclerosis, Hepatol Int; ePub 2018 Feb 8; Bridge, et al

Chronic HCV & Early HIV Viral Response to ART, AIDS; ePub 2018 Jan 13; Willis, Cole, et al

Read more in Hepatitis

Women's Health

Age at Menarche and Depression into Adulthood, Pediatrics; ePub 2017 Dec 26; Mendle, et al

Screening to Reduce Fractures in Older Women, Lancet; ePub 2017 Dec 15; Shepstone, et al

Read more in Women's Health

Sexual Health

Treating Urogenital Chlamydia Infection, Is doxycycline superior to azithromycin?

FDA Approves Sexual Desire Disorder Drug, Flibanserin (Addyi) approved to treat premenopausal women

Read more in Sexual Health

Dermatology

Comparing Oral Meds for Toenail Fungal Infection, JAMA; 2018 Jan 23/30; Kreijkamp-Kaspers, et al

Do Bleach Baths Reduce Atopic Dermatitis Severity?, Ann Allergy Asthma Immunol; 2017 Nov; Chopra, et al

Read more in Dermatology