Commentary

SPRINTing Toward a Systolic Answer

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I am happy to report that my alert SPRINT subject grasped the point rather quickly. As a retired engineer, he understood the importance of obtaining definitive data rather than relying forevermore upon the best guesses of well-meaning experts in the field. Clinical guidelines are useful as far as they go, but they are heavily dependent upon the generation of clinically valid data from randomized clinical trials. My SPRINT subject left the clinic with a renewed commitment to getting his systolic blood pressure down to the assigned goal of 120 mm Hg. All of us should follow his example and try mightily to keep in mind the distinction between clinical guidelines and actual data generated from randomized clinical trials.

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