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Open Clinical Trials for Veterans With Suicidal Ideation

Federal Practitioner. 2019 October;36(6)s:S12-S13

Providing access to clinical trials for veteran patients can be a challenge, but a significant number of trials are now recruiting patients from those patient populations. The VA Office of Research and Development alone sponsors or cosponsors > 1000 trials. The clinical trials listed below are all open as of September 27, 2019 and are focused exclusively on suicide among US veterans. For additional information and full inclusion/exclusion criteria, please consult clinicaltrials.gov.

Intranasal Ketamine for Suicidal Ideation in Veterans

To address the significant need for effective treatment of suicidal ideation in veterans, this trial is designed as an open label pilot study of intranasal ketamine in 15 people.

ID: NCT03788694
Sponsor: Bronx Veterans Medical Research Foundation, Inc
Contact: Rachel Harris, MA, rachel.harris6@va.gov; Marianne Goodman, MD, marianne.goodman@va.gov
Location: James J. Peters VA Medical Center, Bronx, New York


Couples Intervention to Improve Mental Health

Over the last decade, suicide rates have risen within the military and have remained high. Converging evidence suggests that suicide prevention efforts may be enhanced by explicitly including family members in treatment. The study’s objectives are to test the effect of the CCRP, a targeted single session couples intervention on suicide ideation among military service members and veterans, and to understand how the use of the CCRP impacts suicide risk during the 6 months immediately postdischarge from a psychiatric inpatient unit.

ID: NCT04084756
Sponsor: Wesleyan University
Contact: Alexis May, PhD, amay01@wesleyan.edu
Location: Salt Lake Behavioral Health, Utah


Clinical and Imaging Trial of Uridine for Veterans With Suicidal Ideation

This is a randomized, double-blind, placebo-controlled study of the investigational drug uridine as a treatment for suicidal ideation in veterans. The investigators hypothesize that the administration of a naturally occurring dietary supplement, uridine, will rapidly reduce suicidal ideation in veterans. The purpose of this study is to determine whether 4 weeks of uridine supplementation is an effective treatment for suicidal ideation in veterans, when compared to a group taking a placebo.

ID: NCT03265964
Sponsor: VA Office of Research and Development
Contact: Douglas G Kondo, MD, douglas.kondo@va.gov; Danielle Boxer, MS, danielle.boxer@utah.edu
Location: VA Salt Lake City Health Care System, Utah