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Treatment of Ampicillin-Resistant Enterococcus faecium Urinary Tract Infections

There was no statistically significant difference between amoxicillin and nitrofurantoin for the treatment of ampicillin-resistant Enterococcus faecium urinary tract infections.
Federal Practitioner. 2015 June;32(6):20-23
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Conclusion

Although this was a very small retrospective analysis, to the authors knowledge this is the first clinical study supporting the in vitro theory that amoxicillin (500 mg every 8 hours) may overcome the MIC of resistant isolates due to achievement of higher urinary concentrations. Because this was a small retrospective analysis, more prospective evidence is needed to confirm these results.

Acknowledgements
Heather Kim, biostatistician, University of Illinois at Chicago. CCTS Support: UL1RR029879.

Author disclosures
The authors report no actual or potential conflicts of interest with regard to this article.

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