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Hereditary Hypotrichosis Simplex of the Scalp

Cutis. 2017 July;100(1):E12-E14
July 25, 2017|Dermatology
Ronda S. Farah, MD;Heather M. Holahan, MD;Molly S. Moye, MD;Mary S. Stone, MD;Brian L. Swick, MD
Author and Disclosure Information

Dr. Farah is from the Department of Dermatology, University of Minnesota, Minneapolis. Dr. Holahan is from the Department of Dermatology, Rutgers Robert Wood Johnson Medical School, Somerset, New Jersey. Dr. Moye is from Forefront Dermatology, Louisville, Kentucky. Drs. Stone and Swick are from the Department of Dermatology, University of Iowa, Iowa City.

The authors report no conflict of interest.

Correspondence: Ronda S. Farah, MD, Department of Dermatology, University of Minnesota, 516 Delaware St SE, Minneapolis, MN 55455 (rfarah@umn.edu).

Practice Points

  • Hereditary hypotrichosis simplex (HHS) is a rare form of hypotrichosis that typically presents in school-aged children as worsening hair loss localized to the scalp.
  • Historically, HHS has been largely regarded as autosomal dominant, with variable severity also described within families.
  • There is no effective treatment of HHS. Due to potential phenotypic variation, patients should be counseled that they may experience progressive or possible total loss of scalp hair by the third decade of life.

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