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Beaded Papules Along the Eyelid Margins

Cutis. 2016 October;98(4):E1-E3
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Histologically, deposition of eosinophilic homogeneous material is seen around the blood vessels and sweat glands as well as in the dermis and dermoepidermal junction (Figure 4).1,5 Although most patients with LP have a slowly progressive benign course that stabilizes in early adult life, some morbidities and complications may occur (eg, rarely upper respiratory tract involvement can progress and require tracheostomy). There presently is no cure for LP, but some drugs (eg, oral dimethyl sulfoxide, etretinate, acitretin, penicillamine) and laser ablation/dermabrasion of papules are helpful in some cases.1,7

Figure 4. Histopathologic examination of a papule on the lower lip mucosae showed perivascular deposition of eosinophilic homogeneous material (A and B)(both periodic acid–Schiff, original magnifications ×100 and ×200).

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