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EARLY LIFE STRESS AND DEPRESSION Childhood trauma may lead to neurobiologically unique mood disorders

Current Psychiatry. 2005 October;04(10):14-30
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Adults with a history of child abuse or neglect may respond differently than other depressed patients to the usual treatments.

Related resources

  • Depression and Bipolar Support Alliance. www.dbsalliance.org.
  • National Clearinghouse on Child Abuse and Neglect. https://nccanch.acf.hhs.gov.
  • Charney DS, Nemeroff CB. The peace of mind prescription: An authoritative guide to finding the most effective treatment for anxiety and depression. Boston: Houghton Mifflin, 2004.

Drug brand name

  • Nefazodone • Serzone

Disclosure

Dr. Gillespie reports no financial relationship with any company whose products are mentioned in this article or with manufacturers of competing products.

Dr. Nemeroff receives research grants from or is a consultant/speaker for Abbott Laboratories, Acadia Pharmaceuticals, American Foundation for Suicide Prevention, AstraZeneca Pharmaceuticals, Bristol-Myers Squibb Co., Corcept Therapeutics, Cyberonics, Cypress Biosciences, Eli Lilly and Co., Forest Laboratories, GlaxoSmithKline, Janssen Pharmaceutica, Merck & Co., Neurocrine Biosciences, Otsuka Inc., Pfizer Inc., Sanofi Aventis, and Wyeth.

Acknowledgement

Supported by NIH MH-42088, MH-52899 (CBN), and NIH NCRRM01-RR00039 to Emory University.