From the Editor
Commentary
Is evolution’s greatest triumph its worst blunder?
Of all the dazzling achievements of evolution, the most glorious by far is the emergence of the advanced human brain, especially the prefrontal...
Commentary
The accelerating societal entropy undermines mental health
According to the second law of thermodynamics, it is inevitable that entropy will continue to increase over time.
From the Editor
From neuroplasticity to psychoplasticity: Psilocybin may reverse personality disorders and political fanaticism
One of psychiatry’s long-standing dogmas is that personality disorders are enduring, unchangeable, and not amenable to treatment with potent...
From the Editor
Reversing depression: A plethora of therapeutic strategies and mechanisms
Despite much progress, major depressive disorder (MDD) continues to be a challenging and life-threatening neuropsychiatric disorder. It is highly...
From the Editor
3 steps to bend the curve of schizophrenia
Schizophrenia is arguably the most serious psychiatric brain syndrome. It disables teens and young adults and robs them of their potential and...
From the Editor
A PSYCHIATRIC MANIFESTO: Stigma is hate speech and a hate crime
Having witnessed the devastating impact of stigma on patients with mental illness throughout my psychiatric career, I am fed up and disgusted with...
From the Editor
The neurobiology of Jeopardy! champions
As a regular viewer of Jeopardy! I find it both interesting and educational. But the psychiatric neuroscientist in me marvels at...
From the Editor
Sexual activity alters the microbiome, with potential psychiatric implications
Evidence is strong that sexual partners transmit microbiota (bacteria, viruses, fungi, protozoa, and archaea) to each other. While microbial flora...
From the Editor
Beyond diabetes: The beneficial uses of metformin in psychiatry
Metabolic dysregulation is quite common among psychiatric patients, especially those with psychotic or mood disorders. Obesity, diabetes, and...
From the Editor
It’s time for moonshot thinking in psychiatry
“I believe that this nation should commit itself to achieving the goal, before the decade is out, of landing a man on the Moon and returning him...
From the Editor
Is anosognosia a delusion, a negative symptom, or a cognitive deficit?
Anosognosia is the lack of awareness of a disabling physical or mental illness. The term was coined by Joseph Babinski in 1914...