Alzheimer's & Cognition
Feature
Seminal, highly anticipated Alzheimer’s trial falters
Negative top-line results for the phase 2/3 Dominantly Inherited Alzheimer’s Network–Trials Unit study of gantenerumab and solanezumab are...
From the Journals
APOE genotype directly regulates alpha-synuclein accumulation
Two studies synergistically show how the APOE4 genotype is associated with cognitive decline in patients with Lewy body dementia.
From the Journals
Dietary flavonol intake linked to reduced risk of Alzheimer’s
A class of polyphenols found in fruits and vegetables was associated with lower rates of Alzheimer’s in an observational study, setting the stage...
From the Journals
Genetic factor linked to impaired memory after heading many soccer balls
Findings, while preliminary, may be evidence of “early subclinical effects” in those with high levels of ball-heading exposure.
Feature
Cognitive screening of older physicians: What’s fair?
A new report leads to questions about how to standardize the process rather than have a piecemeal institutional approach and whether to focus less...
Conference Coverage
Could preventing dementia be as simple as following your mom’s advice?
SAN DIEGO – Emerging evidence agrees: Lots of exercise, a good diet, and social interaction are good for both body and mind.
Conference Coverage
Pimavanserin reduced dementia-related psychotic symptoms without affecting cognition
SAN DIEGO – The adverse event profile of the second-generation antipsychotic appears more benign than that typically seen with antipsychotics in...
Conference Coverage
Positive functional results reported for aducanumab in a pooled, post hoc analysis
SAN DIEGO – The results might give patients “an extra year or 2” of independence, said one clinical investigator in an aducanumab trial.
Conference Coverage
Intensive BP control reduced dementia but increased brain atrophy and hurt cognition
SAN DIEGO – The small but significant ill effects worried some researchers at the Clinical Trials on Alzheimer’s Disease...
From the Journals
‘Brain enhancement’ supplements sold online may illegally contain piracetam
So-called cognitive enhancement supplements sold online may contain high doses of the nootropic drug piracetam.
From the Journals
Alzheimer’s disease subtypes follow neuropathologic patterns seen in the nucleus basalis of Meynert