Alzheimer's & Cognition
Literature Review
Accounting for sex may improve diagnosis of amnestic MCI
The rate of diagnostic error when applying criteria that account for age and education, but not sex, is approximately 20%.
From the Journals
How does alcohol intake affect dementia risk in older adults?
The association may be more consistently adverse in adults with mild cognitive impairment.
Literature Review
Migraines linked to higher risk of dementia
People with a history of migraines may be at greater risk of developing Alzheimer’s disease and dementia.
Literature Review
Two genetic variants modify risk of Alzheimer’s disease
Common variants in the microglia-specific MS4A gene cluster modify risk for late-onset Alzheimer’s disease and modulate extracellular soluble...
From the Journals
Midlife hypertension is associated with subsequent risk of dementia
Elevated blood pressure in midlife is associated with risk of subsequent dementia, but whether the risk is treatable is unclear.
Conference Coverage
Signals of gut microbiome interaction with experimental Alzheimer’s drug prompt new trial
LOS ANGELES – The first reporting of microbiome data in an Alzheimer’s drug trial opens the door for further investigation of this new endpoint....
Feature
Sleep aids and dementia: Studies find both risks and benefits
LOS ANGELES – Researchers found differences in dementia risk by race and sex; a possible mechanism of damage from certain sleep-promoting...
Conference Coverage
Benzodiazepines, hypnotics don’t increase Alzheimer’s pathology
LOS ANGELES – The drugs were not associated with Alzheimer’s pathology, but were associated with a trend toward greater loss of neurons in the...
From the Journals
Researchers examine potential causes of dementia in CTE
More years of football play were associated with white matter changes and tau accumulation, which were associated with increased risk of dementia...
From the Journals
Hemoglobin levels are associated with long-term dementia risk
Both low and high levels of hemoglobin are linked with an increased risk of dementia, according to a population-based study of adults in the...
Conference Coverage
Large genetic cohort supports NfL as Alzheimer’s biomarker
LOS ANGELES – Mutation carriers in the world’s largest early onset AD cohort saw significant increases in neurofilament light (NfL) from age 22...