Reduced intensity conditioning doesn’t protect fertility

“Male puberty is relatively well preserved after both myeloablative and reduced intensity conditioning, but there is a greater than 90% risk of male infertility associated with both reduced intensity and myeloablative conditioning for HSCT,” Dr. Oquendo del Toro said.

For females, the study paints a different picture. “We saw decreased premature ovarian failure after reduced intensity conditioning … but the fertility potential as assessed by anti-Müllerian hormone was decreased” after both conditioning regimens, she said.

Dr. Oquendo del Toro reported having no conflicts of interest.
 

koakes@mdedge.com

SOURCE: Oquendo del Toro H et al. The 2018 BMT Tandem Meetings, Abstract 88.