Does Leptin Protect Against Dementia?

Overweight and obesity (central adiposity) during middle age and later have been linked to a woman’s chances of developing dementia. Some research has shown that high levels of leptin—a hormone of adipose tissue—may lower the risk of dementia. But in the Prospective Population Study of Women, a longitudinal cohort study in Gothenburg, Sweden, leptin did not seem to be related to dementia.