Argyria Associated With Use of Systemic Colloidal Silver

Homeopathy and home remedies have been utilized for ages. One such modality is silver, which in the past has been purported as a cure for multiple illnesses. More recently, treatment with colloidal silver has been brought to national attention due to a patient named Paul Karason, who has made appearances on several television programs due to his unusual skin discoloration.(1-3) Karason has a condition known as argyria—a blue-gray coloring of the skin caused by accumulation of metallic silver and silver sulfide in the sub-epithelial portions of the skin.(4)