Clinical Review

Argyria Associated With Use of Systemic Colloidal Silver

Author and Disclosure Information

Homeopathy and home remedies have been utilized for ages. One such modality is silver, which in the past has been purported as a cure for multiple illnesses. More recently, treatment with colloidal silver has been brought to national attention due to a patient named Paul Karason, who has made appearances on several television programs due to his unusual skin discoloration.(1-3) Karason has a condition known as argyria—a blue-gray coloring of the skin caused by accumulation of metallic silver and silver sulfide in the sub-epithelial portions of the skin.(4)


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