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Aspirin Did Not Cut CV Risk in Younger Diabetics : At the same time, the data suggest that low-dose aspirin may reduce total events in older patients.

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“We may need to rethink the guidelines,” she suggested, “especially for patients younger than 65.

“To come up with recommendations we also need to assess the risk/benefit ratio,” she continued.

“Diabetes is a high-risk group for cardiovascular events, and Japanese patients are a high-risk group for the use of aspirin because of their risk of hemorrhagic stroke. Conducting this study in Japan, therefore, makes sense. … The safety [in JPAD] was quite reasonable for low-dose aspirin,” she said.