Hematology
Conference Coverage
BCL11A-directed gene therapy advances in sickle cell disease
ORLANDO – A phase 2/3 study is planned to assess the gene therapy in a larger group of patients with sickle cell disease.
Conference Coverage
ASH releases guidelines on managing cardiopulmonary and kidney disease in SCD
ORLANDO – ASH has released the first of five new sets of sickle cell disease guidelines, with the first focusing on screening and management of...
Conference Coverage
Phase 2 studies show potential of FcRn blockade in primary ITP
ORLANDO – The results support continued investigation in phase 3 trial for rozanolixizumab and efgartigimod, according to investigators.
Conference Coverage
New ASH guideline: VTE prophylaxis after major surgery
ORLANDO – The chair of VTE guidelines panel presented highlights of the latest guidelines in a special session at the annual meeting of the...
Conference Coverage
Oral arginine emerges as potential adjuvant for vaso-occlusive crisis management
ORLANDO – Researchers called for a phase 3, multicenter clinical trial to further evaluate the treatment.
Conference Coverage
NFIX could be a target for sickle cell therapy
ORLANDO – Preclinical research suggests it may be a fetal hemoglobin repressor.
Conference Coverage
Fragmentation of sickle cell disease care starts in young adulthood
ORLANDO – Imagine what that would be like to have a chronic, debilitating illness and to have to go to multiple different hospitals, during this...
News from the FDA/CDC
FDA approves Oxbryta for sickle cell disease treatment
The drug, which is approved for adults and children aged 12 years and older, improved hemoglobin in the HOPE trial.
Feature
Survey: Cancer-related pain, opioid use up since 2018
Almost half of patients with cancer did not use anything to manage related symptoms, according to an ASCO poll.
News from the FDA/CDC
FDA approves anemia treatment for transfusion-dependent beta thalassemia patients
Luspatercept-aamt (Reblozyl) is approved for adults with beta thalassemia who require regular red blood cell transfusions.
News
U.S. deaths from preventable causes occur more often in rural areas
In 2017, 21.7% of cancer deaths in the most rural counties were potentially preventable, compared with 3.2% in the most urban counties.