Prostate cancer: Preoperative mpMRI PI-RAD score is linked to upstaging

Key clinical point: A higher preoperative multiparametric magnetic resonance imaging (mpMRI) Prostate Imaging Reporting and Data System (PI‐RADS) score is associated with upstaging on surgical pathology in patients with prostate cancer.

Major finding: PI-RADS score was greater than 3 in 87% of patients. Upstaging was reported in 47% of patients. PI-RADS was an independent risk predictor for upstaging (adjusted odds ratio, 2.034; P < .001).

Study details: A retrospective study of 294 patients with prostate cancer who underwent a prostate mpMRI and radical prostatectomy between 2016 and 2020.

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Disclosures: No funding source was identified for this work. The authors declared no conflict of interests.

Source: Pockros B et al. Prostate. 2021 Dec 8. doi: 10.1002/pros.24280.