The Clinical Picture

Giant nodules on the hands

A 78-year-old man with hyperuricemia treated with allopurinol presents with asymptomatic nodules on both hands. What is the most likely diagnosis...

The Clinical Picture

Palpable purpura

A healthy 47-year-old woman presents with a 3-day history of widespread asymptomatic lesions in the extremities, fever, arthralgias, and mild...

The Clinical Picture

Thick skin on the back

An obese woman with long-standing uncontrolled type 2 diabetes mellitus presents with indurated thickening of the skin on her back. What is the...