Celiac disease: Managing a multisystem disorder

This autoimmune disorder can cause symptoms that involve not only the gastrointestinal tract but also the skin and bones.

The Clinical Picture

Stellate ulceration in a nonuremic patient

Calciphylaxis is a poorly understood small-vessel vasculopathy most often associated with end-stage renal disease.

IM Board Review

Ankle pain in a young woman with Gaucher disease

Gaucher disease causes hepatomegaly, splenomegaly, bone marrow disease, bone pain, bone infarcts, and lytic lesions.