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Herpes zoster boosts short-term stroke, TIA risk


Key clinical point: Herpes zoster is associated with significantly increased short-term risk of stroke/TIA.

Major finding: Adults aged 18-49 years were threefold more likely than controls to experience stroke or TIA within a month of herpes zoster diagnosis.

Study details: This retrospective study included 23,339 U.S. adults with herpes zoster and twice as many matched controls.

Disclosures: The study was sponsored by GlaxoSmithKline and presented by a GSK employee.

Source: Rausch DA. ACC 18



Dr. Rausch’s study was sponsored by her employer, GlaxoSmithKline. The findings are supportive of an earlier study by other investigators, who found that the risk of hospitalization for stroke was up to twofold greater within the first 90 days after diagnosis of HZ in patients with rheumatoid arthritis and other autoimmune diseases than the stroke rate 366-730 days after HZ (Arthritis Rheumatol. 2017.69[2]:439-46).

SOURCE: Rausch DA. ACC 18

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