Open Clinical Trials for Diabetes Mellitus Harm Reduction

Self-efficacy, Beliefs and Adherence—Pilot and Feasibility Trial of a Pharmacist-led Intervention

This study uses an intervention mixed methods design. The overall purpose is to improve medication adherence and assess the clinical impact on diabetes outcomes among patients with uncontrolled diabetes. We will examine if usual care combined with a clinic-based health literacy/psychosocial support intervention improves medication adherence compared to usual care alone. A randomized controlled trial will be conducted at William S. Middleton Memorial Veterans Hospital in Madison, targeting individuals with
uncontrolled diabetes. The patient-centered health literacy intervention will focus on enhancing patients’ self-efficacy and addressing patients’ negative beliefs in medicine and illness.

ID: NCT03406923
Sponsor: University of Wisconsin, Madison
Location: William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin

Practical Telemedicine to Improve Control and Engagement for Veterans With Clinic-Refractory Diabetes Mellitus (PRACTICE-DM)

Diabetes generates significant morbidity, mortality, and costs within the Veterans Health Administration (VHA). Veterans with persistently poor diabetes control despite clinic-based care are among the highest-risk diabetes patients in VHA, and contribute disproportionately to VHA’s massive burden of diabetes complications and costs. VHA critically needs effective, practical management alternatives for veterans whose diabetes does not respond to clinic-based management. The proposed study will address this need by leveraging VHA’s unique Home Telehealth capacity to deliver comprehensive telemedicine-based management for veterans with persistently poor diabetes control despite clinic-based care. Because this intensive intervention is delivered using only existing Home Telehealth workforce, infrastructure, and technical resources—which are ubiquitous at VHA centers nationwide—it could represent an effective, practical approach to improving outcomes in veterans with PPDM, potentially translating to a substantial reduction in VHA’s diabetes burden.

ID: NCT03520413
Sponsor: VA Office of Research and Development
Locations: Durham VA Medical Center, North Carolina; Hunter Holmes McGuire VA Medical Center, Richmond, Virginia

Cooking for Health

Type 2 diabetes is a leading cause of morbidity and mortality among American Indians in the US. Although healthy diet is a key component of diabetes management programs, many American Indians face contextual barriers to adopting a healthy diet including: difficulty budgeting for food on low-incomes, low literacy and numeracy when purchasing food, and limited cooking skills. The proposed project will develop, implement, and evaluate a culturally-targeted healthy foods budgeting, purchasing, and cooking skills intervention aimed at improving the cardio-metabolic health of American Indians with type 2 diabetes who live in rural areas.

ID: NCT03699709
Sponsor: University of Washington
Location: Missouri Breaks Industries Research, Eagle Butte, South Dakota