Open Clinical Trials for Diabetes Mellitus Harm Reduction
Providing access to clinical trials for native American, veteran, and active-duty military patients can be a challenge, but a significant number of trials are now recruiting from those populations. Many trials explicitly recruit patients from the US Department of Veterans
Affairs (VA), the military, and Indian Health Service. The VA Office of Research and Development alone sponsors more than 480 research initiatives, and many more are sponsored by Walter Reed National Medical Center and other major defense and VA facilities. The clinical trials listed below are all open as of October 24, 2018; have at least 1 VA, DoD, or IHS location recruiting patients; and are focused on preventing diabetes mellitus or improving patient care. For additional information and full inclusion/exclusion criteria, please consult clinicaltrials. gov.
Diabetes Prevention Program Outcomes Study (DPPOS)
The Diabetes Prevention Program (DPP) was a multicenter trial examining the ability of an intensive lifestyle or metformin to prevent or delay the development of diabetes in a high risk population due to the presence of impaired glucose tolerance (IGT). The DPP has ended early demonstrating that lifestyle reduced diabetes onset by 58% and metformin reduced diabetes onset by 31%.
ID: NCT00038727
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases
Location: George Washington University, Rockville, Maryland
Efforts to Improve Diabetes Control
The primary objectives of this study are: (1) test the longterm effectiveness of a peer mentor model on improving glucose control, blood pressure, LDL levels, diabetes mellitus quality of life, and depression scores in a mixed race population of poorly controlled diabetic veterans; (2) test the effectiveness of using former peer mentees as peer mentors as a means of creating a self-sustaining program; and (3) test the effects of becoming a mentor on those who were originally mentees given a growing literature that being a mentor is good for your health. Secondary objectives include: (1) in those randomized to being a mentee, explore mentor characteristics associated with improved HbA1c.
ID: NCT01651117
Sponsor: VA Office of Research and Development
Location: Corporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania
A Patient-Centered Strategy for Improving Diabetes Prevention in Urban American Indians
The goal of the proposed research is to identify effective patient-centered strategies to prevent diabetes in high-risk populations in real world settings. The investigators will accomplish this by conducting a randomized controlled trial comparing an enhanced Diabetes Prevention Program addressing psychosocial stressors to a standard version in a high-risk population of urban American Indian
and Alaskan Native peoples within a primary care setting.
ID: NCT02266576
Sponsor: Stanford University
Locations: Timpany Center of San Jose State University, California; Stanford University School of Medicine, California
