Open Clinical Trials for Diabetes Mellitus Harm Reduction

Physical Activity and Participation

Physical activity is the cornerstone of good diabetes management, and yet effective physical activity intervention is not available. The investigators developed a lifestyle intervention based on individual’s home activity patterns. The goal of the study is to test the efficacy of this intervention among veterans with diabetes in a randomized-controlled trial. In addition to physical activity, the investigators will also assess if the intervention will improve social participation among veterans.

ID: NCT02268916
Sponsor: VA Office of Research and Development
Location: VA Ann Arbor Healthcare System, Michigan

Caring Others Increasing EngageMent in PACT (CO-IMPACT)

This trial will compare two methods of increasing engagement in care and success in diabetes management, among patients with diabetes with high-risk features, who also have family members involved in their care.

ID: NCT02328326
Sponsor: VA Office of Research and Development
Locations: VA Ann Arbor Healthcare System, Michigan;VA Pittsburgh Healthcare System, Pennsylvania

STEP UP to Avert Amputation in Diabetes (STEP UP)

This study will evaluate a comprehensive tailored behavioral intervention aimed to improve foot self-care and self-monitoring (combined with dermal thermometry) to prevent recurrent ulcers in Veterans at highest risk of amputation. This intervention may be a novel strategy for improving self-care and early detection of foot abnormalities in this at-risk population using psychological theories to target multiple health behaviors simultaneously. This could be an efficient and cost-effective approach to improve diabetes-related foot health behavior, and other risk factors in patients who are vulnerable to devastating consequences related to amputation.

ID: NCT02356848
Sponsor: VA Office of Research and Development
Location: Manhattan Campus of the VA NY Harbor Healthcare System

Physical Activity Behavior Change for Older Adults After Dysvascular Amputation (PABC)

This pilot study will use mobile-health technology to deliver an intervention designed for lasting physical activity behavior change. The study will assess the feasibility of using the Physical Activity Behavior Change (PABC) intervention for Veterans with lower limb amputation. This intervention will be delivered using wrist-worn wearable activity sensors and a home-based tablet computer to allow real-time physical activity feedback and video interface between the participants and the therapist.

ID: NCT02738086
Sponsor: VA Office of Research and Development
Location: Rocky Mountain Regional VA Medical Center, Aurora, Colorado