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10 Triggers of inflammation to be avoided, to reduce the risk of depression

Current Psychiatry. 2015 March;14(3):6-7,15
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According to the World Health Organization, depression is one of the most prevalent serious brain disorders and the No. 1 cause of dis­ability in the world. Preventing or reducing the incidence and preva­lence of depression is therefore a major public health priority.

Posttraumatic stress disorder is the best known clinical model of stress-induced depression and anxiety. The disorder is associated with a signifi­cant increase in pro-inflammatory cytokines and loss of brain tissue.
 

2-fold challenge: Reduce severity of disease, reduce risk before disease
We psychiatrists almost always see patients after they’ve developed depres­sion and other psychiatric disorders in which neuroinflammation is already present. In addition to pharmacother­apy and psychotherapy (both reduce inflammation), educating patients about adopting a healthy lifestyle—not smok­ing, exercising, eating wisely, avoid­ing weight gain, getting enough sleep, maintaining good oral hygiene, and managing stress—might reduce psychi­atric relapse and prolong their life.

We also should be challenged by the fact that the pathways to inflammation, including the 10 I’ve described here, are common among the population at large. Let’s increase our efforts to pre­emptively reduce the risk of brain dis­orders by encouraging parents and their children to adopt a healthy lifestyle and maintain wellness—and thus avoid fall­ing victim to depression.