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Lab tests for psychiatric disorders: Few clinicians are aware of them

Current Psychiatry. 2013 February;12(02):5-7
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There are 273 biomarkers for schizophrenia, but none are included in DSM-5

In the survey I mentioned at the beginning of this editorial, 60.5% of responders predicted that the DSM-6 (approximately a decade from now) will contain laboratory tests for psychiatric diagnosis. They may very well be right!

Table

Biomarkers for schizophrenia

α-1 antitrypsinIL-7
Apolipoprotein A1IL-10
Apolipoprotein A2IL-11
Apolipoprotein BIL-17
Apolipoprotein CIKIM-1
Apolipoprotein HLH
β-2 microglobulinMCP-2
BetacellulinMDC
BDNFMIF
CAMIP-1 α
CalbindinMMP-2
Cancer antigen 125Prolactin
CD5LProstatic acid phosphatase
Complement 3PYY
CortisolSerum amyloid P
CTGFSortilin
EGFRTestosterone
Endothelin 1Thrombopoietin
FerritinTIMP 1
Fetuin ATNF R 2
FSHTrail R3
HaptoglobinTransferrin
ICAM1TSH
IgAVEGF
IgMVitronectin
IL-6 receptor 
BDNF: brain-derived neurotrophic factor; CD5L: CD5 molecule-like; CTGF: connective tissue growth factor; EGFR: epidermal growth factor receptor; FSH: follicle-stimulating hormone; ICAM1: intercellular adhesion molecule 1; IgA: immunoglobulin A; IgM: immunoglobulin M; IL-6 receptor: interleukin 6 receptor; IL-7: interleukin 7; IL-10: interleukin 10; IL-11: interleukin 11; IL-17: interleukin 17; KIM-1: kidney injury molecule-1; LH: luteinizing hormone; MCP-2: monocyte chemotactic protein 2; MDC: mature dendritic cell; MIF: macrophage migration inhibitory factor; MIP-1 α: macrophage inflammatory protein 1 α; MMP-2: matrix metalloproteinase 2; PYY: peptide YY; TIMP 1: TIMP metallopeptidase inhibitor 1; TNF R 2: tumor necrosis factor receptor 2; TSH: thyroid-stimulating hormone; VEGF: vascular endothelial growth factor Source: Reference 3