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When every minute counts: What workup is sufficient for diagnosis under pressure?

Current Psychiatry. 2005 December;04(12):15-30
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Determining an exact diagnosis in the ED is less important than establishing a diagnostic category to guide emergency psychiatric treatment.

A pragmatic workup

Medical illnesses such as delirium, stroke, drug toxicity, or urinary tract infections can trigger or worsen psychiatric illness (Table 1).5 Comorbidities such as diabetes, hypertension, obesity, and heart disease are common in patients with psychiatric disorders, and psychotropics can cause or exacerbate these conditions.

In the high-pressure ED, a sufficient workup for complicated medical conditions lies somewhere between extensive/unnecessary and inadequate. Thus, determining an exact diagnosis is not as important as establishing a diagnostic category to guide emergency treatment.

Think of psychiatric disorders as they are organized in DSM-IV-TR—mood, anxiety, psychotic, substance use/withdrawal/intoxication, cognitive, adjustment, somatoform, and personality disorders—and whether they are primary or secondary to a general medical condition or substance use. For example:

  • Anxiety disorder secondary to a general medical condition means the history, physical exam, or lab reports suggest a medical condition is the direct physiologic cause of the mood disturbance.
  • Methamphetamine-induced psychotic disorder would be the diagnosis if methamphetamines are presumed to be causing a patient’s psychotic symptoms.

Hospitalization. ED staff often develop a treatment plan based on a patient’s clinical picture and a working diagnosis. The plan hinges on deciding if the patient needs to be admitted to the hospital. Admission may be warranted for life-threatening medical conditions or safety issues, such as threats to self or others or inability to care for oneself at home. Other issues come into play—such as starting or changing medications and follow-up to ensure continuity of care—if you decide to discharge the patient.

Even after medical clearance, patients in the psychiatric emergency service may have underlying medical illnesses (Table 2).6

Table 1

Medical disorders that can cause psychiatric symptoms

Medical/toxic disordersExamples
Alcohol and drugs of abuseAmphetamines (including methamphetamine), cocaine, heroin, Jimson weed, ketamine, marijuana, MDMA (‘Ecstasy’), LSD, PCP
Prescription drugsAntibiotics, anticholinergics, anticonvulsants, antihypertensives, benzodiazepines, chemotherapeutic agents, cimetidine, corticosteroids, digitalis, narcotics, propranolol, sleep medications, tricyclic antidepressants
CNS diseaseHypertensive encephalopathy, intracranial aneurysm, metastases, normal pressure hydrocephalus, postictal nonconvulsive status, primary CNS infection, seizure disorders, stroke, subdural hematoma, tumor
InfectionsAcute rheumatic fever, diphtheria, malaria, Legionnaires’ disease, pneumonia, Rocky Mountain spotted fever, sepsis, syphilis, typhoid fever, urinary tract infection
Metabolic/endocrine disordersAdrenal disease, diabetic ketoacidosis, hepatic encephalopathy, hypoglycemia, pituitary dysfunction, renal disease, serum electrolyte imbalances (sodium, potassium, calcium), thyroid disease, vitamin deficiencies, Wilson’s disease
Cardiopulmonary diseaseArrhythmias, congestive heart failure, COPD/asthma, myocardial infarction, pulmonary embolism
MiscellaneousAnemia, lupus, multiple sclerosis, temporal arteritis, vasculitis
Source: Reprinted with permission from Williams ER, Shepherd SM. Medical clearance of psychiatric patients. Emerg Med Clin North Am 2000;18(2):185-90. Copyright 2000, Elsevier.

Table 2

Reasonable medical assessment in psychiatric emergencies

DO
  Obtain a medical history, the best determinant of medical need
  Listen to patients. If they say they have a medical condition, believe them; if they say they don’t, try to believe them
  Thoroughly check vital signs
  Conduct a focused physical examination
  Maintain a high index of suspicion
  Be selective with laboratory testing. Check:
  • thyroid-stimulating hormone in those with known thyroid disease
  • electrolyte levels in volume-depleted patients or those in withdrawal
  • lead levels in high-risk youth
  • urine in elderly patients with acute mental status changes
DON’T
  Order blanket laboratory screening
  Order an ECG in healthy young patients in the absence of clinical findings
  Order chest radiography in the absence of known disease/exposure/symptoms
Source: Reprinted from Currier GW. Medical assessment on the psychiatric emergency service. Psychiatric Issues in Emergency Care Settings 2004;3(July):17, with permission from Cliggott Publishing Group of CMP Healthcare Media. Copyright 2004.

Overwhelming demand

In the study of ED patient preferences,4 one-fifth of patients said they went to the ED because they lacked access to routine mental health care. Therefore, besides psychiatric conditions caused by medical illnesses, ED physicians can see patients with any primary psychiatric diagnosis, including mood and anxiety disorders and psychosis.

Under pressures of time and limited collateral information, ED staff must:

  • individualize psychiatric treatment
  • consider use of medications and/or restraints
  • rule out life-threatening causes for psychiatric symptoms
  • stabilize patients and prevent injury to self and others.

These tasks are becoming increasingly difficult as more and more patients present to emergency rooms. Nationally, ED visits increased from 19 million in 1992 to 108 million in 2000, according to the U.S. Department of Health and Human Services.1

Psychiatric patients are seeking ED care in greater numbers, and the number of those staying longer than anticipated (“boarding”) also has increased, according to a 2004 survey of 340 physicians by the American College of Emergency Physicians, American Psychiatric Association, National Mental Health Association, and National Alliance for the Mentally Ill. Surveyed physicians blamed inadequate Medicaid funding and bed shortages for the increasing ED visits.7

In crowded emergency rooms, where patients wait longer and longer to be seen, the influx of acutely ill psychiatric patients increases the risks of agitation, violence, and injury, as well as litigation.8