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Worsening agitation and hallucinations: Could it be PTSD?

January 2017. 2017 January;50-54,58
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Mr. G, age 57, presents with confusion, hallucinations, and agitation. He has a history of PTSD, depression, anxiety, and lung cancer. What could be causing his psychiatric symptoms?

These preventive measures are important when treating delirium, such as minimizing Mr. G’s use of benzodiazepine and opioids—medications known to contribute to iatrogenic delirium.

A delirium diagnosis portends grave adverse outcomes. Research has shown significant associations with morbidity and mortality, financial and emotional burden, and prolonged hospitalizations. Often, symptoms of delirium persist for months and patients do not recover completely. However, studies have found that when underlying causes are treated effectively, delirium is more likely to be reversible.11

The prompt diagnosis of delirium with good interdisciplinary communication can reduce the risk of these adverse outcomes.12 Consultation-liaison psychiatrists are well positioned to facilitate the diagnoses of delirium and play a role in educating other health care providers of the importance of prevention, early symptom recognition, full workup, and effective treatment of its underlying causes.

Bottom Line

Delirium is a commonly encountered, life-threatening medical condition that requires prompt diagnosis and effective treatment. In patients who present with multi-factorial causes of altered mental status, it is important to cast a wide net, investigating all causes and treating each individually to improve patient outcomes.

Related Resources

  • Dasgupta M, Brymer C. Prognosis of delirium in hospitalized elderly: worse than we thought. Int J Geriatr Psychiatry. 2014;29(5):497-505.
  • Raj YP. Clearing up confusion. Current Psychiatry. 2015;14(3):18-21,28-31.

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Zolpidem Ambien