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Managing preterm birth to lower the risk of cerebral palsy

OBG Management. 2008 April;20(04):32-44
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Think past hypoxia to the interactions of infection, inflammation, pPROM, and white matter disease

For these reasons and because sub-acute intrauterine inflammation may harm the fetus, delivery can be considered after 32 completed weeks of gestation if fetal lung maturity is confirmed. A meta-analysis of four randomized controlled trials that compared intentional delivery with expectant management after pPROM between 30 and 36 weeks of gestation found no difference in neonatal outcomes.32