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She’s hypercaffeinated, and she’s planning to conceive!

OBG Management. 2008 March;20(03):8-15
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Is the patient placing herself at increased risk of miscarriage? The TV tells her that she is.

Self-policing may be at work, too

It’s interesting that many pregnant women appear to “spontaneously” reduce their intake of caffeine from coffee as they advance through the first trimester. In a study of women at 4 weeks of pregnancy, median caffeine consumption was 350 mg/day; as the women advanced through the first trimester, median caffeine consumption decreased to approximately 200 mg/day.2

In addition, although 33% of women reported drinking coffee before they became pregnant, only 15% were still drinking coffee near the end of the first trimester.

Take pregnancy planning beyond caffeine, of course

For women who are planning a pregnancy in the near future, moderating caffeine consumption is just one, relatively small, aspect of a multifaceted strategy to best plan their pregnancy. When one of your patients tells you that she is preparing to become pregnant, keep in mind for discussion the broader list of key areas that you can tell her to focus on (TABLE 2).That list includes

  • achieving BMI in the normal range
  • ensuring adequate intake of folic acid
  • updating immunizations as appropriate
  • testing for HIV infection
  • assessing the effects of current prescription medications on a pregnancy
  • reducing alcohol intake
  • stopping cigarette smoking and recreational psychoactive drugs.

Every pregnancy—and every child— is precious. Thoughtful preparation to enhance the outcome of pregnancy is an effort well spent.

To that end, “all things in moderation” remains a useful adage.

TABLE 2

“Avoidance” advice for women who want to optimize fertility and pregnancy outcome

HARMFUL EXPOSURE OR LIFESTYLE CHOICEADVICE FOR THE FEMALE PARTNER
Cigarette smokingStop smoking
Elevated (>25) body mass index (BMI)Achieve optimal BMI (18 to 25)
AlcoholMinimize alcohol intake
CaffeineLimit caffeine intake to 250 mg/day or less (approximately)
Excessive exerciseFor a woman who has an optimal BMI, limiting exercise may improve fertility
Source: Barbieri RL. The initial fertility consultation: recommendations concerning cigarette smoking, body mass index and alcohol and caffeine consumption. Am J Obstet Gynecol. 2001;185:1168–1173.
Fertility may take a hit from caffeine, too

In addition to the potential for a modest increase in pregnancy loss, a high level of caffeine intake may also have a modest effect on extending the number of months a couple must try to conceive before the woman becomes pregnant. In a study of 3,187 couples in Europe who were attempting conception, researchers noted the following 9.5 months into their attempt: 16% of women who did not drink coffee were not yet pregnant and 25% of women who drank more than 5 cups of coffee a day were not yet pregnant.1

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