Decline of clomiphene for PCOS-related infertility
OBG Management. 2005 October;17(10):12-14
October 1, 2005|ObGyn
Author and Disclosure Information
Metformin and aromatase inhibitors may promise fewer spontaneous abortions and multiple gestations
If pharmacologic therapy is chosen:
- Metformin is probably the agent of choice.
- If metformin is not effective as a single agent, an aromatase inhibitor might be considered.
- Alternatively, clinicians might continue to use clomiphene as a first-line agent if they prefer to utilize an FDA-approved medication for ovulation induction.
