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From the Journals
A/T/N system predicts cognitive decline
A test of the new A/T/N research model of dementia predicted rates of cognitive decline within its subgroups over a period of nearly 5 years.
Literature Review
CSF neurofilament light level could aid in diagnosis
The level of neurofilament light in CSF may distinguish frontotemporal dementia from other dementias and Parkinson’s disease from atypical...
Video
Patient registry sheds light on the economic impact of MS
SEATTLE – Dr. Kottil Rammohan discusses the extent to which multiple sclerosis limits patients’ potential at work and at home.
From the Journals
COPD exacerbations associated with poor sleep quality
After 18 months of follow-up, patients with at least one exacerbation of COPD had a median baseline Pittsburgh Sleep Quality Index score of 6.0,...
From the Journals
Pediatric-onset MS may slow information processing in adulthood
Scores on the Symbol Digit Modalities Test begin to diverge after age 30 years between MS patients depending on age of onset.
Conference Coverage
In MS, the challenges for women are unique
SEATTLE – In treating women with MS, sexuality, pregnancy, and menopause all require specific attention.
Conference Coverage
In MS, children aren’t just little adults
SEATTLE – Pediatric research is sparse, a neurologist says, but adult options for MS seem to work.
From the Journals
Novel genetic therapy reduces key protein in Huntington’s disease
Intrathecal therapy was associated with dose-dependent reductions in mutant huntingtin protein, but clinical change will require further study.
Feature
Preprints come to medicine: medRxiv launches with safeguards
The new repository of preprints in medicine is intended for researcher-to-researcher communication before publication in peer-reviewed journals....
Conference Coverage
Mutant huntingtin and neurofilament light are potential biomarkers in Huntington’s disease
PHILADELPHIA – The biomarkers successfully distinguish between healthy controls, patients with premanifest disease,...
Literature Review
Induced seizures as effective as spontaneous in identifying epileptic generator
“This finding might lead to a more time-efficient intracranial presurgical investigation of focal epilepsy by reducing the need to record...