Cellular Therapy
From the Journals
Allele-matching in cord blood transplant yields better survival
Matching down to the allele level in umbilical cord blood transplantation between unrelated donors results in greater overall survival for those...
News
All FDA panel members go thumbs up for CTL019 in relapsed/refractory childhood ALL
Steps need to be taken to mitigate the risk of cytokine release syndrome and neurologic events and the potential for secondary malignancies.
Conference Coverage
Tool indicates fracture risk after HSCT
MADRID – Bone health could be assessed earlier using FRAX, ideally at or before the time of the transplant.
Conference Coverage
Ibrutinib dons new anti-GVHD hat
MADRID – Talk about versatility: Ibrutinib (Imbruvica), a drug with marked activity against B-cell malignancies, also appears to be a safe and...
Conference Coverage
Patch is early indicator of temperature rise after HSCT
A wearable patch detected temperature spikes in hospitalized leukemia patients.
Conference Coverage
Stem cell therapy significantly improves ulcer healing
PORTLAND, ORE. – Treating chronic venous leg ulcers with mesenchymal stem cells and fibrin spray significantly improved wound healing.
Commentary
Fighting in a passive manner active against Clostridium difficile
Bezlotoxumab might improve the outcome of patients with C. difficile enteritis.
Conference Coverage
Chronic GVHD linked to fivefold increase in squamous cell skin carcinomas
PORTLAND – Nonmelanoma skin cancers may be a higher risk with GVHD than has previously been quantified.
Conference Coverage
Cord blood/placental cell combo induces rapid immune recovery
MONTREAL – The probability of 1-year survival in children with severe diseases requiring stem cell transplants was 81%.
From the Journals
Optimum antithymocyte globulin exposure after HTC affects survival
Optimum antithymocyte globulin exposure after allogeneic hemopoietic cell transplantation plays an important role in survival.
Conference Coverage
Biomarker algorithm sharpens GVHD treatment outcomes prediction
ORLANDO – A biomarker algorithm was better than was clinical response at predicting outcomes after 1 week of systemic steroid treatment for graft-...