Melanoma
From the Journals
Patients lack confidence in their skin self-exam abilities
While most patients were willing to use teledermoscopy to assist them in self-exams, they still preferred to rely on regularly scheduled physician...
Clinical Review
Advanced Melanoma: First-line Therapy
From the Journals
Systemic therapies are impacting melanoma’s prognostic factors
Systemic treatments have altered the disease kinetics for patients with melanoma.
Conference Coverage
ENCORE-601: Entinostat/pembrolizumab safe, active for melanoma
ATLANTA – Combined therapy with the HDAC inhibitor entinostat and the PD-1 inhibitor pembrolizumab has significant clinical activity and...
Conference Coverage
Consider 9-mm surgical margins for MIS
WAIKOLOA, HAWAII – The widely utilized 5-mm surgical margins for excision of melanoma in situ are inadequate.
Conference Coverage
Novel immunostimulant combo shows early efficacy
SAN FRANCISCO – A one-two approach to stimulating both innate and adaptive immunity appears to be paying off, suggest early efficacy data from a...
Conference Coverage
Antibiotics gut checkpoint inhibitor efficacy
SAN FRANCISCO – Patients who had received antibiotics more than a month before a checkpoint inhibitor had significantly worse survival, regardless...
Conference Coverage
31-GEP test predicts likelihood of metastasis for cutaneous melanoma
WASHINGTON – “By using this one test, it’s able to separate out melanomas that otherwise may be grouped in together under current AJCC staging.”...
Conference Coverage
Diet appears to play an important role in response to anti-PD-1 cancer immunotherapy
Diet appears to affect response to anti-PD-1 cancer immunotherapy, likely by its effect on the gut microbiome.
News
FDA approves pembrolizumab for completely resected melanoma
Approval was based on improved recurrence-free survival in a randomized, double-blind, placebo-controlled, trial of 1,019 patients with completely...
From the Journals
Checkpoint inhibitors ‘viable treatment option’ in HIV-infected individuals
There were no concerning immune-mediated toxicities or changes in HIV-related parameters observed among 73 patients with HIV infection who had...