Conference Coverage

Reduced intensity conditioning doesn’t protect fertility


 

REPORTING FROM THE 2018 BMT TANDEM MEETINGS


“Male puberty is relatively well preserved after both myeloablative and reduced intensity conditioning, but there is a greater than 90% risk of male infertility associated with both reduced intensity and myeloablative conditioning for HSCT,” Dr. Oquendo del Toro said.

For females, the study paints a different picture. “We saw decreased premature ovarian failure after reduced intensity conditioning … but the fertility potential as assessed by anti-Müllerian hormone was decreased” after both conditioning regimens, she said.

Dr. Oquendo del Toro reported having no conflicts of interest.

SOURCE: Oquendo del Toro H et al. The 2018 BMT Tandem Meetings, Abstract 88.

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