Chimeric antigen receptor (CAR) T-cell therapy is one of the hottest advances in lymphoma treatment, but who should get it and what does the process look like? Dr. Allison Winter helps answer those questions as she joins Blood & Cancer host Dr. David H. Henry to break down the side effects and look ahead to possible off-the-shelf products. In Clinical Correlation, Dr. Ilana Yurkiewicz, discusses optimism bias. She recalls a time when a patient’s drive for optimism affected what she told them and whether that was a good or bad thing.