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Higher Methotrexate Dose Fends Off Pediatric Leukemia Recurrence

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FROM THE ANNUAL MEETING OF THE AMERICAN SOCIETY OF CLINICAL ONCOLOGY

A new wrinkle, Dr. Larsen noted, is that the Children’s Oncology Group and the adult Cancer and Leukemia Group B are planning a joint trial comparing adult and children’s regimens for teens and young adults with ALL. It was scheduled to use the Capizzi regimen but needs to be reconsidered.

The National Institutes of Health provided funds for the trial. Two co-authors said they received research funding from Becton-Dickinson.