Diabetes and CVD: To Be, Or Not to Be, Aggressive?

Based on these results, it is fair to conclude that the evidence supports a comprehensive risk-reduction strategy addressing most risk factors in diabetes. However, such a strategy should include consideration of possible hazards of aggressive therapy. As always, the benefit:risk ratio should be carefully evaluated for each individual patient. We should remember the old maxim and Hippocratic oath, that above all we should do no harm.