When used for the appropriate indication and with proper technique, nearly all chemical peeling agents have demonstrated excellent clinical efficacy and remain an indispensable cost-effective tool for dermatologists, according to a recent review. Researchers conducted a comprehensive search for relevant literature investigating chemical peeling agents and provided an up-to-date analysis of all currently available chemical peels for dermatologic use, as well as a step-by-step instructional protocol for an algorithmic approach to treatment. In addition, they performed a search of all commercially available, prescription-based peeling agents in order to identify all products currently available in the US market. Although chemical peels are the third most commonly performed noninvasive cosmetic procedure in the US, there has been a paradigm shift in recent years, with lasers largely supplanting deep peels. Despite this, superficial peels have proliferated in both popularity and product diversity.
Soleymani T, Lanoue J, Rahman Z. A Practical Approach to Chemical Peels: A review of fundamentals and step-by-step algorithmic protocol for treatment. J Clin Aesthet Dermatol. 2018;11(8):21-28.