A Rare Case of Segmental Neurofibromatosis With Multiple Blue-Red Pseudoatrophic Plaques
Cutis. 2014 September;94(3):149-152
September 8, 2014|Cutis
Author and Disclosure Information
We report the case of a 5-year-old girl who presented with 2 blue-red atrophic plaques on the left leg as well as subcutaneous nodules that were present since infancy. Although the clinical criteria of neurofibromatosis (NF) were absent, microscopic examination revealed features of a blue-red neurofibroma.
Practice Points
- Biopsy should be considered for pseudoatrophic patches to perform early diagnosis of neurofibroma-tosis (NF), which is rare.
- Blue-red or cerulean macules, especially if associated with skin atrophy, are highly suggestive of neurofibroma in a patient affected by NF.
Conclusion
Segmental NF is characterized by an unusual clinical onset of multiple and localized pseudoatrophic plaques in the absence of the common clinical features of NF. We recommend that pseudoatrophic patches undergo histologic examination for early diagnosis of rare cases of NF with such an unusual presentation.
